世界杯2022官网投注

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董界
发布时间:2021/07/13   阅读量:


 

 

个人简介

董界,博士/特聘副教授/硕士生导师,2012年本科毕业于中南大学,2017年博士毕业于世界杯2022官网投注药物化学系。2019年5月获批澳门大学“濠江博士后”计划,于澳门大学“中药质量研究国家重点实验室”进行博士后研究工作,2021年6月进入世界杯2022官网投注工作。主要从事药物化学和化学信息学领域内相关问题研究。近期发表SCI论文32篇,第一作者或通讯作者13篇,其中多篇发表于领域内TOP期刊,被引用800多次。专注于领域内网络分析计算平台构建相关数据库设计与应用科学软件包和工具开发;人工智能与数据挖掘,药物分子设计等。已发表10多个计算平台和数据库,获得7项软件著作权。主持国家自然科学青年基金1项,湖南省自然科学青年基金1项,参与国家重点研发计划、国家自然科学基金多项。

 

研究方向

基于AI的计算机辅助分子设计

化学信息学计算平台及数据库的开发

 

近年课题:

主持国家自然科学青年基金项目:基于机器学习方法的甜味剂多层次虚拟评价系统的构建研究。

主持湖南省自然科学基金青年基金项目:基于化学信息学方法的甜味剂虚拟筛选平台的构建与应用。

作为骨干参与国家重点研发计划子课题:食品安全监管大数据体系构建

 

近期主要论文:

Dong J, Zhu M F, Yun Y H, et al. BioMedR: An R/CRAN package for integrated data analysis pipeline in biomedical study. [J]. Briefings in Bioinformatics. 2019.

Yang ZY#, Dong J#, Yang ZJ, et al. ChemFLuo: a web-server for structure analysis and identification of fluorescent compounds. [J]. Briefings in Bioinformatics. 2020.

J Dong, HL Gao, D Ouyang. PharmSD: A novel AI-based computational platform for solid dispersion formulation design. International Journal of Pharmaceutics, 2021, 120705

Gao H#, Wang W#, Dong J#, et al. An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 158: 336-346.

Yang Z F, Xiao R, Luo F J, … Dong J*, et al. Food Bioactive Small Molecule Databases: Deep Boosting for the Study of Food Molecular Behaviors[J]. Innovative Food Science & Emerging Technologies, 2020: 102499.

Dong J, Cao D S, Miao H Y, et al. ChemDes: an integrated web-based platform for molecular descriptor and fingerprint computation[J]. Journal of Cheminformatics, 2015, 7(1): 1-10.

Dong J#, Yao Z J#, Wen M, et al. BioTriangle: a web-accessible platform for generating various molecular representations for chemicals, proteins, DNAs/RNAs and their interactions[J]. Journal of Cheminformatics, 2016, 8(1): 1-13.

Dong J, Yao Z J, Zhu M F, et al. ChemSAR: an online pipelining platform for molecular SAR modeling[J]. Journal of Cheminformatics, 2017, 9(1): 1-13.

Dong J, Yao Z J, Zhang L, et al. PyBioMed: a python library for various molecular representations of chemicals, proteins and DNAs and their interactions [J]. Journal of Cheminformatics, 2018, 10(1): 16.

Dong J#, Wang N N#, Yao Z J, et al. ADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database[J]. Journal of Cheminformatics, 2018, 10(1): 29.

Wang N N#, Dong J#, Zhang L, et al. HAMdb: a database of human autophagy modulators with specific pathway and disease information[J]. Journal of Cheminformatics, 2018, 10(1): 34.

Dong J#, Wang N N#, Liu K Y, et al. ChemBCPP: A freely available web server for calculating commonly used physicochemical properties[J]. Chemometrics and Intelligent Laboratory Systems, 2017, 171: 65-73.

Wang N N#, Dong J#, Deng Y H, et al. ADME properties evaluation in drug discovery: prediction of Caco-2 Cell permeability using a combination of NSGA-II and boosting[J]. Journal of Chemical Information and Modeling, 2016, 56(4): 763-773.

Yao Z J#, Dong J#, Che Y J, et al. TargetNet: a web service for predicting potential drug-target interaction profiling via multi-target SAR models[J]. Journal of Computer-Aided Molecular Design, 2016, 30(5): 413-424.

 

联系方式:

Google scholar: https://scholar.google.com/citations?user=phFGEecAAAAJ&hl=zh-CN

E-mail: biomed@csu.edu.cn

办公地址:长沙市岳麓区桐梓坡路172号湘雅医学院孝骞楼622